Intravital Microscopy
Brain
IVIM Technology provides advanced imaging solutions that support a wide range of intravital imaging applications in the brain. With our cutting-edge technology and expertise, we empower researchers to delve deep into the complexities of brain biology and pathology. With IVIM Technology, you will gain valuable insights into brain structure, function, and pathology, hence advancing our understanding of neurological disorders and informing the development of new treatments and therapies. Here's how IVIM Technology can support your brain intravital imaging needs:
Brain
Day 7
Vessel / BBB leakage
Day 14
Day 21
Brain
Sham
Apoptotic body
Vessel
Neuroinflammation
Apoptotic body
Vessel
Brain
Day 4
Neutrophil/Macrophage
Vessel
Day 10
Longitudinal In Vivo Imaging of Cellular-level Dynamic Phenotype Changes Inside the Living Body
- IVIM Technology’s contract R&D service provides high-quality repetitive observations using imaging chambers.
- Repetitive intravital imaging of cellular-level dynamics & tissue remodeling inside the living body in vivo will provide you with new insight in the processes of human disease development.
Dynamic Changes in Brain Disease Models
- Changes in BBB
- penetrationChanges in target accumulation in brain tissue
- Changes in cortical capillaries, vascular permeability & vessel diameter
- Changes in pericyte coverage
- Immune cell recruitment to inflammatory / damaged spot
- Tissue cell apoptosis & phagocytosis
In Vivo Imaging of Drug Delivery & Clearance at Target Cells & Tissues
IVIM Technology’s contract R&D service provides a direct imaging analysis of delivery to target tissue and cells, efficacy, and mode of action (MOA) of new therapeutic candidates in microscopic cellular-level in various preclinical model of human disease.
BBB penetration & delivery to brain tissue•
Target disease : Neurodegenerative disease, Stroke, etc.
Brain, Cortex
Control
BBB penetrating meterial
Vessel
Drug
Drug
Brain, Cortex
Control
BBB penetrating meterial
Drug
Drug
IVM Imaging for Brain Research
- Neurovascular Interactions
- Microglial Dynamics
- Brain Development
- Neurodegenerative Diseases
- Brain Tumor Imaging
- Blood-Brain Barrier (BBB) Imaging
- Neuroimmune Interactions
- Drug Delivery and Efficacy