Intravital Microscopy
According to data from regulatory authorities, the acceptance rate of new drug candidates has been stuck at around 10 percent worldwide for the last few decades. Determining the validation, tracking, and mode of action (MOA) of new drug candidates at the preclinical development stage in vivo, is vital for the effectiveness and authorization of the new drug.
IVIM Technology continuously optimizes its products with thehelp of its engineers and the know-how gained in the field by itsapplication specialists. IVIM Technology provides reliable results for validating the ADME, drug delivery/efficacy and MOA studies in the early stages of new drug development processes.
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Objective Lens Rotation System
Optimizing images of curved samples, such as the brain, can be challenging when trying to fit the sample surface perpendicular to the objective lens through sample rotation. IVIM Technology offers a solution with an objective lens rotation system that adjusts the incident angle of the excitation light to the sample.
The rotation arm of this system can rotate 140° along each of the X, Y, and Z axes, enabling the objective lens to be positioned at various angles relative to the sample. This system allows for precise alignment of the objective lens with the sample surface without needing to rotate the sample itself.
Retina Imaging System
Imaging the retina in vivo with a conventional microscope is challenging due to light refraction as it passes through the eye's lens. IVIM Technology offers a specialized system designed for imaging the retina of animal models. This system enables the observation of cellular dynamics in the retina and cornea of live animals.
Endo-Microscopy System
- Endo-Microscopy is a useful tool for minimal invasive imaging of internal organs that cannot be penetrated by light.
- IVIM Technology can provide a customized intravital microscopy system and the GRIN lens-based endoscope for um-level high resolution endo-microscopic imaging.
Free Space (FS) System
- Various approaches are required for intravital imaging depending on the target organ, research purpose, and needs of the researcher.
- IVIM Technology can provide a FS-(Free Space) system, a flexible intravital microscopy that can meet the needs of individual users.
- The FS-system opens the area near the objective lens, so that users can freely use it accordingly.
- Also, we can provide the options below for the FS system:
- High speed Z axis piezo scanner instead of an objective turret
- Large sample stage for rat, rabbit, etc.
- Attachable accessories for experiments on the side plate
- Anything else that is deemed possible after consultatio
