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Technology of Intravital Microscopy

IVIM Technology's pioneering All-in-One intravital microscopy platform is a pivotal solution capable
of probing the intricate dynamic behaviors of countless cells within living organisms. It represents a cutting-edge core technology poised to uncover the underlying pathophysiology of diverse human diseases and facilitate the discovery of new treatments.

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Products

  • IVM-C3

    IVM-C3

    Tractable, Fast, Gentle

    IVM-C3 is a highly integrated system for in vivo imaging, offering significantly enhanced detection efficiency, optical resolution, and image contrast compared to conventional fluorescence microscopy.

  • IVM-M3

    IVM-M3

    Deep Tissue Imaging, High-Resolution, Tunable

    IVM-M3 seamlessly combines the flexibility of a traditional converted microscope with the high-resolution imaging capabilities of second-harmonic generation microscopy.

  • IVM-CM3

    IVM-CM3

    High Contrast, High Resolution, Dual-mode, Tunable

    IVM-CM3 delivers exceptional contrast and resolution with its tunable Two-Photon laser unit, allowing focus on desired wavelengths ranging from as low as 690 nm to higher up to 1050 nm, and everything in between.

  • IVM-MS3

    IVM-MS3

    Compact, Cost-Saving, Hands-Free

    IVM-MS3 represents thesmart evolution of IVM-M3, an All-in-One Two-Photon Intravital Microscopy system meticulously optimized for in vivo imaging.

  • IVM-CMS3

    IVM-CMS3

    Cost-Effective, Straightforward, Dual-Mode

    IVM-CMS3 stands out as the world's most compact and affordable dual-mode intravital confocal and two-photon microscope, offering versatile functionality in a single, streamlined box.

  • IVM-FS

    IVM-FS

    Practical, Customizable

    The IVM-FS system offers the same functions as the IVM-CMS3 system, with the key difference being its larger stage and modules, designed to accommodate animals larger than mice and rats (older than 6 weeks), such as ferrets, rabbits, and others. With the dark curtain provided, there's no need for a dedicated dark room or specific space just for the microscope.

IVM-C3 (Confocal v.3)

IVM-C3 (Confocal v.3)

IVM-C3 is a highly integrated system for in vivo imaging, offering significantly enhanced detection efficiency, optical resolution, and image contrast compared to conventional fluorescence microscopy. With a 4-wavelength laser and four high-sensitivity confocal detectors, IVM-C3 enables multi-dimensional views of living cells and tissues in 3D or 4D, while supporting up to four different colors.

Key Features

Tractable Fast Gentle

Bone Marrow

Transplanted cell Vessel (CD31)

IVM-C3 (Confocal v.3)

Bone Marrow

Transplanted cell Vessel (CD31)

IVM-C3 (Confocal v.3)

Bone Marrow

Transplanted cell Vessel (CD31)

IVM-C3 (Confocal v.3)

IVM-M3 (Two-Photon v. 3)

DeepTissueImaging,High-resolution, Tunable

IVM-M3 (Two-Photon v. 3)

IVM-M3 seamlessly combines the flexibility of a traditional converted microscope with the high-resolution imaging capabilities of second-harmonic generation microscopy. Featuring a fully automated tunable fs-pulse NIR laser system, IVM-M3 excels in deep tissue imaging by using less-scattering NIR wavelengths. The comprehensive control functionality of the fs- laser system is integrated with the two-photon imaging software, ensuring user convenience with various automation algorithms. Experience advanced imaging with IVM-M3 for your research needs.

Key Features

Deep Tissue Imaging High-Resolution Tunable
IVM-M3 (Two-Photon v. 3)
IVM-M3 (Two-Photon v. 3)
IVM-C3

IVM-CM3 (ConfocalandTwo-Photon v. 3)

IVM-CM3 (ConfocalandTwo-Photon v. 3)

IVM-CM3 delivers exceptional contrast and resolution with its tunable Two-Photon laser unit.It allows focus on samples at desired wavelengths ranging from as low as 690 nm to as high as  1050 nm, and everything in between. This cutting-edge system seamlessly combines the strengths of both Confocal and Two-Photon microscopy, offering limitless possibilities for three- dimensional imaging of living cells whether near the skin or deep within tumors in small animals. Explore the potential of IVM-CM3 for advanced and versatile imaging in your research.

Key Features

High Contrast High Resolution Dual-mode Tunable

Liver

Fibrotic collagen Hepatocyte

IVM-CM3 (ConfocalandTwo-Photon v. 3)

Fibrotic collagen Hepatocyte

IVM-CM3 (ConfocalandTwo-Photon v. 3)

Fibrotic collagen Hepatocyte

IVM-CM3 (ConfocalandTwo-Photon v. 3)
IVM-M3

IVM-MS3 (Two- Photon Smart v.3)

IVM-MS3 (Two- Photon Smart v.3)

IVM-MS3 represents thesmart evolution of IVM-M3, an All-in-One Two-Photon Intravital Microscopy system meticulously optimized for in vivo imaging. This system seamlessly integrates a compact, high-stability, and maintenance-free fs-pulse laser unit into a single box. With the ability to focus on deep tissues at a fixed wavelength of 920nm, IVM- MS3 serves as an exceptional resource for researchers with specific targets, offering optimal functionality within limited resources and budget constraints. Explore the possibilities with IVM-MS3 for efficient and budget-friendly in vivo imaging.

Key Features

Compact Cost-Saving Hands-Free

Skin

Transplanted cell Transplanted cell Vessel (CD31)

IVM-MS3 (Two- Photon Smart v.3)

Large Intestine

Immune cell Mamnose (anti-inflammation) Blood vessel (EB)

IVM-MS3 (Two- Photon Smart v.3)

Kidney

H2B (Nuclei) ROSA-mT/mG Blood vessel (EB)

IVM-MS3 (Two- Photon Smart v.3)
IVM-CM3

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

IVM-CMS3 stands out as the world's most compact and affordable dual-mode intravital confocal and two-photon microscope, offering versatile functionality in a single, streamlined box. Leveraging the confocal laser units from IVM-C3 and the compact two-photon laser unit from IVM-MS3, IVM-CMS3 features a one-switch (one-click) mode changing capability, providing convenient multi-purpose use for intravital functional imaging while optimizing space and minimizing costs. Explore the efficient and cost-saving capabilities of IVM-CMS3 for your diverse imaging needs.

Key Features

Cost-Effective Straightforward Dual-Mode

Skin

CAG-RFP Collagen (SHG)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

Liver

Collagen (SHG) Lipid Droplet (SF44)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

Muscle

Sarcomere (SHG) Vessel (CD31) Nerve (Thy1)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)
IVM-MS3

IVM-FS (Free-Space)

Practical, Customizable

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

The IVM-FS system offers the same functions as the IVM-CMS3 system, with the key difference being its larger stage and modules, designed to accommodate animals larger than mice and rats (older than 6 weeks), such as ferrets, rabbits, and others. With the dark curtain provided, there's no need for a dedicated dark room or specific space just for the microscope.

Key Features

Practical and Customizable - Tailored to Your Research Needs
IVM-CMS3

CRO Services

IVIM Technology's CRO Service offers a gateway to accelerate drug development through advanced intravital in vivo imaging.
Our mission is to revolutionize drug development by providing more than just a service - we offer a strategic partnership to propel your projects toward success.

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Events

  • Upcoming Webinar

    26 Jun 2025

    event demo

    (EN) From Antibody Therapeutics to ADCs: Imaging Analysis Using Intravital Microscopy

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Upcoming Webinar

    03 Jul 2025

    event demo

    (JP) 生体顕微鏡による脳疾患の経過と治療効果の 可視化 : 長期追跡研究への応用

    Learn more
  • Past Webinar

    19 Jun 2025

    event demo

    (KR) 항체치료제에서 ADC까지: Intravital microscopy을 활용한 이미징 분석

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Workshop

    06 Jan 2025

    event demo

    Real-time Confocal and Two-Photon Microscopy

    Learn more
  • Workshop

    27 Nov 2024

    event demo

    차세대 신약 개발 세미나

    Learn more
  • Workshop

    30 Oct 2024

    event demo

    AI/ 고급정밀 기술 기반 생체 내 기전 분석

    Learn more
  • Exhibition

    03 May 2025 - 07 May 2025

    event demo

    AAI 2025: American Association of Immunology

    Learn more
  • Exhibition

    25 Apr 2025 - 30 Apr 2025

    event demo

    AACR 2025: American Association of Cancer Research

    Learn more
  • Exhibition

    21 Jan 2025 - 23 Jan 2025

    event demo

    AIM 2025: Advanced Imaging Methods

    Learn more
  • Upcoming Webinar

    26 Jun 2025

    event demo

    (EN) From Antibody Therapeutics to ADCs: Imaging Analysis Using Intravital Microscopy

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Upcoming Webinar

    03 Jul 2025

    event demo

    (JP) 生体顕微鏡による脳疾患の経過と治療効果の 可視化 : 長期追跡研究への応用

    Learn more
  • Past Webinar

    19 Jun 2025

    event demo

    (KR) 항체치료제에서 ADC까지: Intravital microscopy을 활용한 이미징 분석

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Workshop

    06 Jan 2025

    event demo

    Real-time Confocal and Two-Photon Microscopy

    Learn more
  • Workshop

    27 Nov 2024

    event demo

    차세대 신약 개발 세미나

    Learn more
  • Workshop

    30 Oct 2024

    event demo

    AI/ 고급정밀 기술 기반 생체 내 기전 분석

    Learn more
  • Exhibition

    03 May 2025 - 07 May 2025

    event demo

    AAI 2025: American Association of Immunology

    Learn more
  • Exhibition

    25 Apr 2025 - 30 Apr 2025

    event demo

    AACR 2025: American Association of Cancer Research

    Learn more
  • Exhibition

    21 Jan 2025 - 23 Jan 2025

    event demo

    AIM 2025: Advanced Imaging Methods

    Learn more
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