Publications

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Oxidative stress-induced astrocytic collagen biosynthesis drives glial barrier formation and neuronal death in ischemic stroke

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Label-free volumetric refractive-index imaging of fibrillar collagen architecture, assembly, and cell-associated remodeling

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Skin-derived G-CSF activates pathological granulopoiesis upon psoriasis

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Heterogeneous Evolution of Pancreatic Cancer Microvasculature Revealed by Longitudinal Intravital Imaging

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Label-free quantitative 3D mapping of collagen architecture by holotomography

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Programmable spatial coherence tomography: diffraction-limited three-dimensional reflection imaging under modulated monochromatic illumination

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AAVrh32.33 capsid demonstrates unexpected dermal tropism regardless of immunodominant epitope

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Incoherent dielectric tensor tomography for quantitative three-dimensional measurement of biaxial anisotropy

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Lilii bulbus Exerts Anti-Seizure Effects by Modulating GABAergic Synapse Organization in the Pentylenetetrazol Kindling Model

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Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs

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Seleno-Amino Acid Nanotherapeutics Upregulates Selenoproteins to Inhibit Oxidation and Neuroinflammation for Spinal Cord Injury Recovery

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Polymersomes preventing brain infiltration of CD177+ neutrophils to mitigate hemorrhagic transformation post-tPA thrombolysis

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Alcohol-induced oxidative stress triggers mitochondrial Ca2+ release through the permeability transition pore

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circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

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Quantitative rFRC-based evaluation of computational resolution enhancement in in vivo two-photon subcellular imaging

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Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin

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HEV-Targeted Antibody-Drug Conjugate Promotes Long-Term Cardiac Allograft Acceptance

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Slippery dopamine–fluoropolymer hybrid surface for improving biliary stent longevity

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Rapid Replenishment of Phylloquinone in the Plasma and Liver Using Hyaluronan-Based Nanocapsules Reverses Endothelial Dysfunction in Mice

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A Chemically Engineered Macrocyclic Peptide Shuttle Overcomes Blood-Brain Barrier in Aging Brain

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Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity

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Computational Resolution Enhancement of Mitochondria monitoring in Multiple Organs using Intravital Two-Photon Microscopy

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Sequential Mitochondrial Transplantation for Myocardial Ischemia-Reperfusion Injury Treatment

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Regulation of lipoprotein processing by GPNMB in foamy macrophages: potential therapeutic targets for atherosclerosis

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Targeting P2Y14R alleviates platelet-induced NET formation and venous thrombosis through PKA/AKAP13/RhoA axis

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Renal cancer cell-derived amphiregulin recruits mesenchymal stromal cells, induces their glycolytic switch, and promotes tumour growth

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Synergistic targeting of MCL1 and caspases for enhanced anti-tumor immunity in breast cancer

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Matrix Stiffness Promotes DRP1-Mediated Myofibroblast Senescence to Drive Silica-Induced Pulmonary Fibrosis

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BMAL1 modulation alleviates inflammatory responses in monocytes by targeting the Fis1- mediated mitochondrial unfolded protein response in high-altitude hypoxia

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Cocklebur-inspired magnetic nanomotors for targeted thrombus therapy

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Transporting via Neutrophil as a Key Mechanism for Nanoparticle Redistribution to Tumor and Spleen

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Comparative Evaluation of Combined Denoising and Resolution Enhancement Algorithms for Intravital Two-Photon Imaging of Organs

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Impaired coronary flow reserve by hyperviscosity in a mouse model of non-light chain multiple myeloma: a mechanism of coronary flow impairment at the capillary level

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Ultrasmall inorganic nanoparticles repair damaged meningeallymphatic vessels to boost Parkinson’s disease therapy

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Elucidating the role of Campylobacter concisus–derived indole metabolites in gut inflammation and immune modulation

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Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics

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Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis

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Bioengineered nanovesicles for efficient siRNA delivery through ligand-receptor-mediated and enzyme-controlled membrane fusion

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qPulmoFib Imaging: A novel quantitative evaluation method based on optical imaging technology for precise staging and early diagnosis of idiopathic pulmonary fibrosis in animal models

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Binge drinking triggers VGLUT3-mediated glutamate secretion and subsequent hepatic inflammation by activatingmGluR5/NOX2 in Kupffer cells

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Neutrophil-derived exosomes promote sepsis-related multiple organ dysfunction through the induction of neutrophil extracellular trap formation

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Discoidal Nanoparticles Exploit Thrombus-Induced Shear Gradients to Enhance Site-Specific Thrombolysis in Stroke

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Multiphoton intravital microscopy in small animals of long-term mitochondrial dynamics based on super‐resolution radial fluctuations

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Increased CSF drainage by non-invasive manipulation of cervical lymphatics

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Rapid Replenishment of Phylloquinone in the Plasma and Liver Using Hyaluronan-Based Nanocapsules Reverses Endothelial Dysfunction in Mice

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Preserving spatial and quantitative information in unpaired biomedical image-to-image translation

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Perivascular Niche–Resident Alveolar Macrophages Promote Interstitial Pneumonitis Related to Trastuzumab Deruxtecan Treatment

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Self-supervised denoising of dynamic fluorescence images via temporal gradient-empowered deep learning

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Inhibiting Immune Crosstalk by Modulation of the Intracellular Function and Extracellular Environment of Diseased Microglia to Boost Parkinson’s Disease Therapy

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FABP4 inhibition suppresses bone resorption and protects against postmenopausal osteoporosis in ovariectomized mice

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Identification of nanoparticle infiltration in human breast milk: Chemical profiles and trajectory pathways

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Near-infrared fluorescent nanoprobe enables noninvasive, longitudinal monitoring of graft outcome in RPE transplantation

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H2O2-induced astrocytic collagen triggers neuronal death via fucosylation-dependent glial barrier formation upon ischemic stroke

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CXCL12+ fibroblastic reticular cells in lymph nodes facilitate immune tolerance by regulating T cell–mediated alloimmunity

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Janus double-sided nanofibrous patch with asymmetric wettability and controlled topical delivery of tryptanthrin and indirubin as an effective therapy for psoriasis

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Artificial Mitochondrial Nanorobots Deliver Energy In Vivo by Oral Administration

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Dapagliflozin, An SGLT2 Inhibitor, Improves Endothelial Cell Energy Metabolism Through Enhanced Mitochondrial Respiration

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Intravital imaging of peritubular microcirculation impairment in cisplatin-induced acute kidney injury

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Programmable ultrasound-mediated swarms manipulation of bacteria–red blood cell microrobots for tumor-specific thrombosis and robust photothermal therapy

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Colon cancer-cell-specific drug delivery by gemcitabine conjugated with peptide chain targeting ENO1

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Off-Target Interactions of Vancomycin with Vascular Wall Involving Elastin-Induced Self-Assembly

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Oxygen nanobubbles of ICG dimers achieve self-cascade photothermal and photodynamic therapy for hypoxia-reversible tumor treatment

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7-nm Mn0.5 Zn0.5Fe2O4 superparamagnetic iron oxide nanoparticle (SPION): a high-performance theranostic for MRI and hyperthermia applications

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Prussian Blue Nanozyme Featuring Enhanced S uperoxide D ismutase - like Activity for Myocardial Ischemia Reperfusion Injury Treatment

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Synthetic Bilirubin-Based Nanomedicine Alleviates Atopic Dermatitis by Reducing Oxidative Stress and Modulating Immune Responses

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Computational Resolution Enhancement for Sub-Cellular Organelles Imaging in Tissues Using Two-Photon Fluorescence Microscopy

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Inhibition of nitric oxide synthase transforms carotid occlusion-mediated benign oligemia into de novo large cerebral infarction

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Biomimetic Vascularized iPSC-Hepatocyte Spheroids for Liver Regeneration

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Cyanobacteria-intelligent biohybrid system enables light-guided tumor-associated macrophage-specific siRNA delivery

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Chemical induction of the interaction between AIMP2-DX2 and Siah1 to enhance ubiquitination

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CD71+erythroid cells promote multiple myeloma progression and impair anti-bacterial immune response

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Redox Oxygen Species-Responsive Nanotheranostics with Dual-Channel Fluorescent Turn-On for Early Diagnosis and Targeted Therapy of Alzheimer's Disease

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Transformable Gel-to-Nanovaccine Enhances Cancer Immunotherapy via Metronomic-Like Immunomodulation and Collagen-Mediated Paracortex Delivery

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Mesenchymal stromal cells restrain the Th17 cell response via L-amino-acid oxidase within lymph nodes

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Reversibly photoswitchable protein assemblies with collagen affinity for in vivo photoacoustic imaging of tumors

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Endothelial Cell-Derived Extracellular Vesicles Promote Aberrant Neutrophil Trafficking and Subsequent Remote Lung Injury

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A male mouse model for metabolic dysfunction-associated steatotic liver disease and hepatocellular carcinoma

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Inhibiting monocyte migration reduces arterial thrombosis and facilitates thrombolysis

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Intravital imaging of cardiac tissue utilizing tissue-stabilized heart window chamber in live animal model

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Myo-inositol trispyrophosphate prevents right ventricular failure and improves survival in monocrotaline-induced pulmonary hypertension in the rat

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Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded protein response during hypobaric hypoxic stress

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Tumor-penetrating iRGD facilitates penetration of poly (floxuridine-ketal)-based nanomedicine for enhanced pancreatic cancer therapy

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Deciphering perivascular macrophages and microglia in the retinal ganglion cell layers

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A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence via inhibiting ferroptosis

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Intravital Imaging of Peritubular Microcirculation Impairment in Cisplatin-Induced Acute Kidney Injury

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GV1001 modulates neuroinflammation and improves memory and behavior through the activation of gonadotropin-releasing hormone receptors in a triple transgenic Alzheimer’s disease mouse model

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Real-Time Live Imaging of Osteoclast Activation via Cathepsin K Activity in Bone Diseases

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Statistically unbiased prediction enables accurate denoising of voltage imaging data

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Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer

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Inhalable siRNA Nanoparticles for Enhanced Tumor-Targeting Treatment of KRAS-Mutant Non-Small-Cell Lung Cancer

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Fabrication of Scratched Nanogrooves for Highly Oriented Cell Alignment and Application as a Wound Healing Dressing

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In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal formation and tubular deterioration in the adenine-induced chronic kidney disease mouse model

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Stabilized two-photon intravital imaging using dexmedetomidine

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Agonistic Tie2 antibody suppresses normal-to-tumor vascular transition in glioblastoma invading zone

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Anticoagulants enhance molecular and cellular immunotherapy of cancer by improving tumor microcirculation structure and function and redistributing tumor infiltrates

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Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice

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Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier

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Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality

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Minimizing Motion Artifacts in Intravital Microscopy Using the Sedative Effect of Dexmedetomidine

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Characterization of junctional structures in the gingival epithelium as barriers against bacterial invasion

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In vivo observation of multi-phase spatiotemporal cellular dynamics of transplanted HSPCs during early engraftment

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Estrogen-Related Receptor g Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism

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Strategies for Targeted Delivery of Exosomes to the Brain: Advantages and Challenges

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Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome

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Calsequestrin 2 overexpression in breast cancer increases tumorigenesis and metastasis by modulating the tumor microenvironment

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Longitudinal Intravital Imaging of Tumor-Infiltrating Lymphocyte Motility in Breast Cancer Models

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Compact Quantum-Dot Microbeads with Sub-Nanometer Emission Linewidth

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Submicrometer perovskite plasmonic lasers at room temperature

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Oral delivery of topotecan in polymeric nanoparticles: Lymphatic distribution and pharmacokinetics

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Exosome-based delivery of super-repressor IkBa ameliorates kidney ischemia-reperfusion injury

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Intravital Laser-scanning Two-photon and Confocal Microscopy for Biomedical Research

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Neutrophils Return to Bloodstream Through the Brain Blood Vessel After Crosstalk With Microglia During LPS-Induced Neuroinflammation

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Delivery of Periodontopathogenic Extracellular Vesicles to Brain Monocytes and Microglial IL-6 Promotion by RNA Cargo

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Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine model for nonalcoholic fatty liver disease

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Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality

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Cricket paralysis virus internal ribosome entry site-derived RNA promotes conventional vaccine efficacy by enhancing a balanced Th1/Th2 response

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Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear- cytoplasmic labeling