Publications 68

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    Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear- cytoplasmic labeling

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    Cricket paralysis virus internal ribosome entry site-derived RNA promotes conventional vaccine efficacy by enhancing a balanced Th1/Th2 response

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    Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality

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    Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine model for nonalcoholic fatty liver disease

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    Delivery of Periodontopathogenic Extracellular Vesicles to Brain Monocytes and Microglial IL-6 Promotion by RNA Cargo

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    Neutrophils Return to Bloodstream Through the Brain Blood Vessel After Crosstalk With Microglia During LPS-Induced Neuroinflammation

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    Oral delivery of topotecan in polymeric nanoparticles: Lymphatic distribution and pharmacokinetics

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    Exosome-based delivery of super-repressor IkBa ameliorates kidney ischemia-reperfusion injury

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    Submicrometer perovskite plasmonic lasers at room temperature

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    Compact Quantum-Dot Microbeads with Sub-Nanometer Emission Linewidth

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    Intravital Laser-scanning Two-photon and Confocal Microscopy for Biomedical Research

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    Longitudinal Intravital Imaging of Tumor-Infiltrating Lymphocyte Motility in Breast Cancer Models

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    Calsequestrin 2 overexpression in breast cancer increases tumorigenesis and metastasis by modulating the tumor microenvironment

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    Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome

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    Strategies for Targeted Delivery of Exosomes to the Brain: Advantages and Challenges

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    Estrogen-Related Receptor g Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism

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    In vivo observation of multi-phase spatiotemporal cellular dynamics of transplanted HSPCs during early engraftment

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    Characterization of junctional structures in the gingival epithelium as barriers against bacterial invasion

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    Minimizing Motion Artifacts in Intravital Microscopy Using the Sedative Effect of Dexmedetomidine

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    Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality

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    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier

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    Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice

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    Anticoagulants enhance molecular and cellular immunotherapy of cancer by improving tumor microcirculation structure and function and redistributing tumor infiltrates

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    An agonistic anti-Tie2 antibody suppresses the normal-totumor vascular transition in the glioblastoma invasion zone

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    Stabilized two-photon intravital imaging using dexmedetomidine

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    In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal formation and tubular deterioration in the adenine-induced chronic kidney disease mouse model

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    Fabrication of Scratched Nanogrooves for Highly Oriented Cell Alignment and Application as a Wound Healing Dressing

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    Inhalable siRNA Nanoparticles for Enhanced Tumor-Targeting Treatment of KRAS-Mutant Non-Small-Cell Lung Cancer

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    Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer

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    Statistically unbiased prediction enables accurate denoising of voltage imaging data

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    Real-Time Live Imaging of Osteoclast Activation via Cathepsin K Activity in Bone Diseases

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    GV1001 modulates neuroinflammation and improves memory and behavior through the activation of gonadotropin-releasing hormone receptors in a triple transgenic Alzheimer’s disease mouse model

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    Intravital Imaging of Peritubular Microcirculation Impairment in Cisplatin-Induced Acute Kidney Injury

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    A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence via inhibiting ferroptosis

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    Tumor-penetrating iRGD facilitates penetration of poly (floxuridine-ketal)-based nanomedicine for enhanced pancreatic cancer therapy

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    Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded protein response during hypobaric hypoxic stress

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    Intravital imaging of cardiac tissue utilizing tissue-stabilized heart window chamber in live animal model

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    Inhibiting monocyte migration reduces arterial thrombosis and facilitates thrombolysis

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    A male mouse model for metabolic dysfunction-associated steatotic liver disease and hepatocellular carcinoma

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    Reversibly photoswitchable protein assemblies with collagen affinity for in vivo photoacoustic imaging of tumors

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    Mesenchymal stromal cells restrain the Th17 cell response via L-amino-acid oxidase within lymph nodes

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    Endothelial Cell-Derived Extracellular Vesicles Promote Aberrant Neutrophil Trafficking and Subsequent Remote Lung Injury

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    Transformable Gel-to-Nanovaccine Enhances Cancer Immunotherapy via Metronomic-Like Immunomodulation and Collagen-Mediated Paracortex Delivery

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    Redox Oxygen Species-Responsive Nanotheranostics with Dual-Channel Fluorescent Turn-On for Early Diagnosis and Targeted Therapy of Alzheimer's Disease

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    CD71+erythroid cells promote multiple myeloma progression and impair anti-bacterial immune response

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    Chemical induction of the interaction between AIMP2-DX2 and Siah1 to enhance ubiquitination

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    Cyanobacteria-intelligent biohybrid system enables light-guided tumor-associated macrophage-specific siRNA delivery

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    Inhibition of nitric oxide synthase transforms carotid occlusion-mediated benign oligemia into de novo large cerebral infarction

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    Synthetic Bilirubin-Based Nanomedicine Alleviates Atopic Dermatitis by Reducing Oxidative Stress and Modulating Immune Responses

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    7-nm Mn0.5 Zn0.5Fe2O4 superparamagnetic iron oxide nanoparticle (SPION): a high-performance theranostic for MRI and hyperthermia applications

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    Off-Target Interactions of Vancomycin with Vascular Wall Involving Elastin-Induced Self-Assembly

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    Intravital imaging of peritubular microcirculation impairment in cisplatin-induced acute kidney injury

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    Artificial Mitochondrial Nanorobots Deliver Energy In Vivo by Oral Administration

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    Deciphering perivascular macrophages and microglia in the retinal ganglion cell layers

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    CXCL12+ fibroblastic reticular cells in lymph nodes facilitate immune tolerance by regulating T cell–mediated alloimmunity

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    Identification of nanoparticle infiltration in human breast milk: Chemical profiles and trajectory pathways

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    Inhibiting Immune Crosstalk by Modulation of the Intracellular Function and Extracellular Environment of Diseased Microglia to Boost Parkinson’s Disease Therapy

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    Near-infrared fluorescent nanoprobe enables noninvasive, longitudinal monitoring of graft outcome in RPE transplantation

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    qPulmoFib Imaging: A novel quantitative evaluation method based on optical imaging technology for precise staging and early diagnosis of idiopathic pulmonary fibrosis in animal models

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    Dapagliflozin, An SGLT2 Inhibitor, Improves Endothelial Cell Energy Metabolism Through Enhanced Mitochondrial Respiration

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    Neutrophil-derived exosomes promote sepsis-related multiple organ dysfunction through the induction of neutrophil extracellular trap formation

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    Myo-inositol trispyrophosphate prevents right ventricular failure and improves survival in monocrotaline-induced pulmonary hypertension in the rat

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    Self-supervised denoising of dynamic fluorescence images via temporal gradient-empowered deep learning

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    Agonistic Tie2 antibody suppresses normal-to-tumor vascular transition in glioblastoma invading zone

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    Colon cancer-cell-specific drug delivery by gemcitabine conjugated with peptide chain targeting ENO1

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    Computational Resolution Enhancement for Sub-Cellular Organelles Imaging in Tissues Using Two-Photon Fluorescence Microscopy

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    Perivascular Niche–Resident Alveolar Macrophages Promote Interstitial Pneumonitis Related to Trastuzumab Deruxtecan Treatment

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    Rapid Replenishment of Phylloquinone in the Plasma and Liver Using Hyaluronan-Based Nanocapsules Reverses Endothelial Dysfunction in Mice