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Newsletter vol.8

10 Dec 2025 English
Introducing the IVM-FS: Advanced Imaging for Rats and Other
IVIM TECHNOLOGY
NEWSLETTER
Volume 8, Sep 2025
Light up your world!
About IVIM Technology, Inc.

Founded in 2017, IVIM Technology is a global leader in turnkey intravital microscopy solutions. Our all-in-one box confocal and two-photon microscope systems enable real-time cellular imaging in live, anesthetized animals—transforming the landscape of in vivo research.

Recognized as one of the Top 10 APAC Bioanalytical Service Providers, IVIM serves a broad network of over 100 institutions worldwide, spanning academia, biotechnology, and the pharmaceutical industry. Our integrated portfolio includes intravital microscopy (IVM) systems, preclinical in vivo imaging solutions, training, specialized accessories, and labeled antibodies—empowering researchers to drive scientific discovery with precision, consistency, and efficiency.

Introducing IVM-FS: Real-Time Cellular Insights

into Rats and Other Medium-Sized Animals

IVIM Technology, known for rapidly advancing solutions in the dynamic field of imaging—supporting a wide variety of live and non-living samples—has introduced its latest innovation: the IVM-FS system. This cutting-edge free-space intravital microscopy platform offers unparalleled flexibility and precision, enabling real-time, high-resolution imaging of medium-sized animals like rats. With its open optical design, advanced motion compensation, and adaptable window setups, the IVM-FS system overcomes traditional challenges in intravital imaging, providing researchers with a versatile and powerful tool for exploring complex cellular dynamics in vivo.

Real-time imaging in rats and other medium-sized animals presents several challenges. Their size makes surgery more invasive, and maintaining stable anesthesia during long sessions is demanding. Thicker tissues limit optical depth, and stronger organ motion increases artifacts, requiring advanced stabilization. Standardized protocols are also less common than in mice, often requiring custom setups. 


IVIM`s new free-space intravital microscopy system, IVM-FS, addresses these challenges. Its open, flexible design supports stable imaging in larger animals, while delivering deep, high-resolution views of dynamic cellular activity—even in thick, moving tissues. With integrated motion compensation and adaptable window setups, IVM-FS makes long-term intravital imaging in rats not just feasible, but highly effectively opening the door to deeper insights into human-relevant models.

Figure: Real-time visualization of B cells, red blood cells, and vascular structures in the inguinal lymph node of an anesthetized rat (check out the time-lapse video here!).
Read the full article here!
Upcoming Webinar – September 24
Intravital Imaging of Rat Organs at Cellular Resolution: Applications in Metabolic Disease Research

Join us for an in-depth look at cutting-edge intravital imaging techniques used to study real-time tissue dynamics, blood flow, and immune responses in live SD rats — a powerful model for metabolic disease research.
Learn More!
Upcoming Events
  • SEP 18-19 | 5th Day of Intravital Microscopy Workshop
  • OCT 23-25 | High-profile Pancreatic Cancer Think Tank Meeting 
  • NOV 5-9 | Society of Immunotherapy of Cancer (SITC) - Exhibition
  • DEC 6-10 | Cell Bio 2025 - Exhibition
and more...
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IVIM Technology
information@ivimtech.com
#A-1305, Hyundai Knowledge Industry Center, 11, Beobwon-ro 11-gil, Songpa-gu, Seoul, 05836, Korea
 Tel: +82-2-431-7450

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