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Technology of Intravital Microscopy

아이빔테크놀로지의 혁신적인 올인원 생체현미경 플랫폼은 살아 있는 동물의 생체 내에서 일어나는 수많은
세포의 복잡한 동적 행동을 탐구할 수 있는 핵심 솔루션입니다. 이 기술은 다양한 인간 질환의 근본적인 병리 생리를 밝혀내고
새로운 치료법 개발을 가능하게 하는 대표적인 최첨단 핵심 기술입니다.

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Products

  • IVM-C3

    IVM-C3

    Tractable, Fast, Gentle

    IVM-C3는 기존 형광 현미경에 비해 감지 효율, 광학 해상도, 이미지 대비를 크게 향상시킨 고도로 통합된 공초점 전용 생체현미경 시스템입니다.

  • IVM-M3

    IVM-M3

    Deep Tissue Imaging, High-Resolution, Tunable

    IVM-M3는 유연성을 지닌 파장 가변형 이광자 현미경으로, 심부 조직 관찰뿐만 아니라 이차조화파를 활용하여 염색 없이 반복된 패턴 관찰이 가능한 모델입니다.

  • IVM-CM3

    IVM-CM3

    High Contrast, High Resolution, Dual-mode, Tunable

    IVM-CM3는 공초점과 이광자 기능이 하나로 결합된 시스템으로, 탁월한 SNR과 해상도를 제공합니다. 이광자 기능을 위해 장착된 펨토초 레이저는 690nm에서 1050nm까지의 범위 내에서 파장을 변환할 수 있습니다.

  • IVM-MS3

    IVM-MS3

    Compact, Cost-Saving, Hands-Free

    IVM-MS3는 지금까지 존재하는 이광자 현미경과는 달리 차별화된 920nm 고정형 펨토초 레이저를 탑재한 올인원 이광자 생체현미경 시스템으로, 사용이 매우 간편하고 성능이 뛰어납니다.

  • IVM-CMS3

    IVM-CMS3

    Cost-Effective, Straightforward, Dual-Mode

    IVM-CMS3는 전 계에서 가장 콤팩트하고 합리적인 공초점 및 이광자 듀얼 모드 생체현미경입니다. 간편한 박스 타입의 올인원 생체현미경으로, 생체현미경에서 요구되는 거의 모든 기능이 탑재된 아이빔테크놀로지의 베스트셀러 모델입니다.

  • IVM-FS

    IVM-FS

    Practical, Customizable

    IVM-FS 시스템은 IVM-CMS3 시스템과 동일한 기능을 제공하지만, in vivo 용 대형 스테이지가 장착된 오픈형 생체현미경으로 생후 6주령 이상의 rat과 그보다 큰 동물(예: 페럿, 토끼 등)을 수용할 수 있도록 설계되어 있습니다.

IVM-C3 (Confocal v.3)

IVM-C3 (Confocal v.3)

IVM-C3 is a highly integrated system for in vivo imaging, offering significantly enhanced detection efficiency, optical resolution, and image contrast compared to conventional fluorescence microscopy. With a 4-wavelength laser and four high-sensitivity confocal detectors, IVM-C3 enables multi-dimensional views of living cells and tissues in 3D or 4D, while supporting up to four different colors.

Key Features

Tractable Fast Gentle

Bone Marrow

Transplanted cell Vessel (CD31)

IVM-C3 (Confocal v.3)

Bone Marrow

Transplanted cell Vessel (CD31)

IVM-C3 (Confocal v.3)

Bone Marrow

Transplanted cell Vessel (CD31)

IVM-C3 (Confocal v.3)

IVM-M3 (Two-Photon v. 3)

DeepTissueImaging,High-resolution, Tunable

IVM-M3 (Two-Photon v. 3)

IVM-M3 seamlessly combines the flexibility of a traditional converted microscope with the high-resolution imaging capabilities of second-harmonic generation microscopy. Featuring a fully automated tunable fs-pulse NIR laser system, IVM-M3 excels in deep tissue imaging by using less-scattering NIR wavelengths. The comprehensive control functionality of the fs- laser system is integrated with the two-photon imaging software, ensuring user convenience with various automation algorithms. Experience advanced imaging with IVM-M3 for your research needs.

Key Features

Deep Tissue Imaging High-Resolution Tunable
IVM-M3 (Two-Photon v. 3)
IVM-M3 (Two-Photon v. 3)
IVM-C3

IVM-CM3 (ConfocalandTwo-Photon v. 3)

IVM-CM3 (ConfocalandTwo-Photon v. 3)

IVM-CM3 delivers exceptional contrast and resolution with its tunable Two-Photon laser unit.It allows focus on samples at desired wavelengths ranging from as low as 690 nm to as high as  1050 nm, and everything in between. This cutting-edge system seamlessly combines the strengths of both Confocal and Two-Photon microscopy, offering limitless possibilities for three- dimensional imaging of living cells whether near the skin or deep within tumors in small animals. Explore the potential of IVM-CM3 for advanced and versatile imaging in your research.

Key Features

High Contrast High Resolution Dual-mode Tunable

Liver

Fibrotic collagen Hepatocyte

IVM-CM3 (ConfocalandTwo-Photon v. 3)

Fibrotic collagen Hepatocyte

IVM-CM3 (ConfocalandTwo-Photon v. 3)

Fibrotic collagen Hepatocyte

IVM-CM3 (ConfocalandTwo-Photon v. 3)
IVM-M3

IVM-MS3 (Two- Photon Smart v.3)

IVM-MS3 (Two- Photon Smart v.3)

IVM-MS3 represents thesmart evolution of IVM-M3, an All-in-One Two-Photon Intravital Microscopy system meticulously optimized for in vivo imaging. This system seamlessly integrates a compact, high-stability, and maintenance-free fs-pulse laser unit into a single box. With the ability to focus on deep tissues at a fixed wavelength of 920nm, IVM- MS3 serves as an exceptional resource for researchers with specific targets, offering optimal functionality within limited resources and budget constraints. Explore the possibilities with IVM-MS3 for efficient and budget-friendly in vivo imaging.

Key Features

Compact Cost-Saving Hands-Free

Skin

Transplanted cell Transplanted cell Vessel (CD31)

IVM-MS3 (Two- Photon Smart v.3)

Large Intestine

Immune cell Mamnose (anti-inflammation) Blood vessel (EB)

IVM-MS3 (Two- Photon Smart v.3)

Kidney

H2B (Nuclei) ROSA-mT/mG Blood vessel (EB)

IVM-MS3 (Two- Photon Smart v.3)
IVM-CM3

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

IVM-CMS3 stands out as the world's most compact and affordable dual-mode intravital confocal and two-photon microscope, offering versatile functionality in a single, streamlined box. Leveraging the confocal laser units from IVM-C3 and the compact two-photon laser unit from IVM-MS3, IVM-CMS3 features a one-switch (one-click) mode changing capability, providing convenient multi-purpose use for intravital functional imaging while optimizing space and minimizing costs. Explore the efficient and cost-saving capabilities of IVM-CMS3 for your diverse imaging needs.

Key Features

Cost-Effective Straightforward Dual-Mode

Skin

CAG-RFP Collagen (SHG)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

Liver

Collagen (SHG) Lipid Droplet (SF44)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

Muscle

Sarcomere (SHG) Vessel (CD31) Nerve (Thy1)

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)
IVM-MS3

IVM-FS (Free-Space)

Practical, Customizable

IVM-CMS3 (Confocal and Two-Photon Smart v. 3)

The IVM-FS system offers the same functions as the IVM-CMS3 system, with the key difference being its larger stage and modules, designed to accommodate animals larger than mice and rats (older than 6 weeks), such as ferrets, rabbits, and others. With the dark curtain provided, there's no need for a dedicated dark room or specific space just for the microscope.

Key Features

Practical and Customizable - Tailored to Your Research Needs
IVM-CMS3

CRO Services

아이빔테크놀로지의 CRO 서비스는 비 임상 시험 단계에서 생체 내 영상화 검증을 통해 약물의 분포와 효능에 대한 직접적인 데이터를 제공합니다. 아이빔테크놀로지는 단순한 서비스 제공을 넘어, 성공적인 프로젝트 추진을 위한 전략적 파트너십을 제공함으로써 연구 개발의 혁신을 추구하고 있습니다.

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Events

  • Past Webinar

    03 Jul 2025

    event demo

    (JP) 生体顕微鏡による脳疾患の経過と治療効果の 可視化 : 長期追跡研究への応用

    Bill Park
    Technical Application Scientist, IVIM Technology
    Learn more
  • Past Webinar

    26 Jun 2025

    event demo

    (EN) From Antibody Therapeutics to ADCs: Imaging Analysis Using Intravital Microscopy

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Past Webinar

    19 Jun 2025

    event demo

    (KR) 항체치료제에서 ADC까지: Intravital microscopy을 활용한 이미징 분석

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Workshop

    26 Feb 2025

    event demo

    생체현미경 기반 생체 내 세포영상기술 및 의생명연구활용

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  • Workshop

    19 Feb 2025

    event demo

    현장데모: 생체현미경 IVM-CMS3

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  • Workshop

    06 Jan 2025

    event demo

    Real-time Confocal and Two-Photon Microscopy

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  • Exhibition

    03 May 2025 - 07 May 2025

    event demo

    AAI 2025: American Association of Immunology

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  • Exhibition

    21 Jan 2025 - 23 Jan 2025

    event demo

    AIM 2025: Advanced Imaging Methods

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  • Exhibition

    06 Nov 2024 - 10 Nov 2024

    event demo

    SITC 2024: Society for Immunotherapy of Cancer Annual Meeting 2024

    Learn more
  • Past Webinar

    03 Jul 2025

    event demo

    (JP) 生体顕微鏡による脳疾患の経過と治療効果の 可視化 : 長期追跡研究への応用

    Bill Park
    Technical Application Scientist, IVIM Technology
    Learn more
  • Past Webinar

    26 Jun 2025

    event demo

    (EN) From Antibody Therapeutics to ADCs: Imaging Analysis Using Intravital Microscopy

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Past Webinar

    19 Jun 2025

    event demo

    (KR) 항체치료제에서 ADC까지: Intravital microscopy을 활용한 이미징 분석

    Jenny Ohm
    Technical Application Scientist, IVIM Technology
    Learn more
  • Workshop

    26 Feb 2025

    event demo

    생체현미경 기반 생체 내 세포영상기술 및 의생명연구활용

    Learn more
  • Workshop

    19 Feb 2025

    event demo

    현장데모: 생체현미경 IVM-CMS3

    Learn more
  • Workshop

    06 Jan 2025

    event demo

    Real-time Confocal and Two-Photon Microscopy

    Learn more
  • Exhibition

    03 May 2025 - 07 May 2025

    event demo

    AAI 2025: American Association of Immunology

    Learn more
  • Exhibition

    21 Jan 2025 - 23 Jan 2025

    event demo

    AIM 2025: Advanced Imaging Methods

    Learn more
  • Exhibition

    06 Nov 2024 - 10 Nov 2024

    event demo

    SITC 2024: Society for Immunotherapy of Cancer Annual Meeting 2024

    Learn more
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