Live Cell Intravital Imaging

Real-time In Vivo Imaging of Cellular-level Dynamic Phenotype Inside the Living Body
  • • IVIM Technology’s contract R&D service provides high-quality observations of cellular-level dynamics in various animal models.
  • • Dynamic 3D imaging of various cellular-level dynamics such as cell trafficking, cell-cell interaction, and cell-microenvironment interaction inside the living body in vivo will provide you a new insight in the processes of human disease development.
Intravascular Movement of Target Cells & Materials In vivo real-time imaging of microcirculation
  • • Microcirculation & dead space measurement
  • • Functional capillary ratio measurement
Tumor
RBC
Vessel
Retina
RBC
Vessel
Lung
RBC
Vessel
Real-time imaging of various cell dynamics in vessels/lymphatics
  • • Immune cells : Leukocyte, lymphocyte, granulocyte, neutrophil, macrophage, monocyte, dendritic cells, T cell, B cell, NK cell, microglial cell, etc.
  • • Tissue cells : Vascular endothelial cells, lymphatic endothelial cell, hepatocyte, kidney cell, astrocyte, pericyte, etc.
  • • Fluorescently labeled tumor cells (Mouse & human cell lines) : Brain/breast/lung/pancreatic cancer, glioblastoma, melanoma, etc.
Lymph node
B cell
T cell
FRC
Tumor
Cancer cell
Stromal cell
Liver
Nanoparticle
Vessel
Lung
Neutrophil
Vessel
Cellular-level Dynamics in Various Tissues In Vivo 4D cell imaging, tracking and interaction monitoring
  • • Cell recruitment
  • • Cell motility, motion of dendrite
  • • Cell-Cell / Cell-Microenvironment interaction
Tumor
Breast cancer cell
T Cell
Vessel
Skin
N⌀/M⌀
Inflammatory protein
Spleen
DC/Monocyte
Vessel
Retina
DC/Monocyte
In Vivo Imaging of Various Organs in Animal Model
+ Thymus, Thyroid gland, Adipose Tissue, Lymphatics, Microcirculation … etc.